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Publikationen

PD Dr. med. C. Kirchmaier

1

Wegert W, Harder S, Bassus S, Kirchmaier CM.

Platelet-dependent thrombin generation assay for monitoring the efficacy of recombinant Factor VIIa. Platelets. 2005 Feb;16(1):45-50. PMID: 15763896 [PubMed - in process]

2

Westrup D, Santoso S, Follert-Hagendorff K, Bassus S, Just M, Jablonka B, Kirchmaier CM.

Glanzmann thrombasthenia Frankfurt I is associated with a point mutation Thr176Ile in the N-terminal region of alpha IIb subunit integrin. Thromb Haemost. 2004 Nov;92(5):1040-51. PMID: 15543332 [PubMed - in process]

3

Bassus S, Mahnel R, Scholz T, Wegert W, Westrup D, Kirchmaier CM.

Effect of dealcoholized beer (Bitburger Drive) consumption on hemostasis in humans. Alcohol Clin Exp Res. 2004 May;28(5):786-91. PMID: 15166655 [PubMed - indexed for MEDLINE]

4

Graff J, Klinkhardt U, Westrup D, Kirchmaier CM, Breddin HK, Harder S.

Pharmacodynamic characterization of the interaction between the glycoprotein IIb/IIIa inhibitor YM337 and unfractionated heparin and aspirin in humans. Br J Clin Pharmacol. 2003 Sep;56(3):321-6. PMID: 12919181 [PubMed - indexed for MEDLINE]

5

Graff J, Klinkhardt U, Schini-Kerth VB, Harder S, Franz N, Bassus S, Kirchmaier CM.

Close relationship between the platelet activation marker CD62 and the granular release of platelet-derived growth factor. J Pharmacol Exp Ther. 2002 Mar;300(3):952-7. PMID: 11861803 [PubMed - indexed for MEDLINE]

6

Harenberg J, Huisman MV, Tolle AR, Breddin HK, Kirchmaier CM.

Reduction in thrombus extension and clinical end points in patients after initial treatment for deep vein thrombosis with the fixed-dose body weight-independent low molecular weight heparin certoparin. Semin Thromb Hemost. 2001 Oct;27(5):513-8. PMID: 11668421 [PubMed - indexed for MEDLINE]

7

Klinkhardt U, Graff J, Westrup D, Kirchmaier CM, Esslinger HU, Breddin HK, Harder S.

Pharmacodynamic characterization of the interaction between abciximab or tirofiban with unfractionated or a low molecular weight heparin in healthy subjects. Br J Clin Pharmacol. 2001 Sep;52(3):297-305. PMID: 11560562 [PubMed - indexed for MEDLINE]

8

Bassus S, Herkert O, Kronemann N, Gorlach A, Bremerich D, Kirchmaier CM, Busse R, Schini-Kerth VB.

Thrombin causes vascular endothelial growth factor expression in vascular smooth muscle cells: role of reactive oxygen species. Arterioscler Thromb Vasc Biol. 2001 Sep;21(9):1550-5. PMID: 11557687 [PubMed - indexed for MEDLINE]

9

Harder S, Klinkhardt U, Graff J, Westrup D, Kirchmaier CM, Glusa E, Mascelli MA, Marciniak SJ, Just A, Losche W, Breddin HK.

In vitro dose response to different GPIIb/IIIa-antagonists: inter-laboratory comparison of various platelet function tests. Thromb Res. 2001 Apr 1;102(1):39-48. PMID: 11323013 [PubMed - indexed for MEDLINE]

10

Seidl C, Siehl J, Ganser A, Hofmann WK, Fischer M, Kirchmaier CM, Hoelzer D, Seifried E.

Platelet glycoprotein expression in patients with myelodysplastic syndrome. Thromb Res. 2000 Oct 1;100(1):27-34. PMID: 11053613 [PubMed - indexed for MEDLINE]

11

Gorlach A, Brandes RP, Bassus S, Kronemann N, Kirchmaier CM, Busse R, Schini-Kerth VB.

Oxidative stress and expression of p22phox are involved in the up-regulation of tissue factor in vascular smooth muscle cells in response to activated platelets. FASEB J. 2000 Aug;14(11):1518-28. PMID: 10928986 [PubMed - indexed for MEDLINE]

12

Klinkhardt U, Kirchmaier CM, Westrup D, Graff J, Mahnel R, Breddin HK, Harder S.

Ex vivo--in vitro interaction between aspirin, clopidogrel, and the glycoprotein IIb/IIIa inhibitors abciximab and SR121566A. Clin Pharmacol Ther. 2000 Mar;67(3):305-13. PMID: 10741635 [PubMed - indexed for MEDLINE]

13

Klinkhardt U, Kirchmaier CM, Westrup D, Breddin HK, Mahnel R, Graff J, Hild M, Harder S.

Differential in vitro effects of the platelet glycoprotein IIb/IIIa inhibitors abixicimab or SR121566A on platelet aggregation, fibrinogen binding and platelet secretory parameters. Thromb Res. 2000 Feb 15;97(4):201-7. PMID: 10674406 [PubMed - indexed for MEDLINE]

14

Kaiser B, Kirchmaier CM, Breddin HK, Fu K, Fareed J.

Preclinical biochemistry and pharmacology of low molecular weight heparins in vivo--studies of venous and arterial thrombosis. Semin Thromb Hemost. 1999;25 Suppl 3:35-42. Review. PMID: 10549714 [PubMed - indexed for MEDLINE]

15

Harder S, Kirchmaier CM, Krzywanek HJ, Westrup D, Bae JW, Breddin HK.

Pharmacokinetics and pharmacodynamic effects of a new antibody glycoprotein IIb/IIIa inhibitor (YM337) in healthy subjects. Circulation. 1999 Sep 14;100(11):1175-81. PMID: 10484537 [PubMed - indexed for MEDLINE]

16

Kronemann N, Bouloumi A, Bassus S, Kirchmaier CM, Busse R, Schini-Kerth VB.

Aggregating human platelets stimulate expression of vascular endothelial growth factor in cultured vascular smooth muscle cells through a synergistic effect of transforming growth factor-beta(1) and platelet-derived growth factor(AB). Circulation. 1999 Aug 24;100(8):855-60. PMID: 10458723 [PubMed - indexed for MEDLINE]

17

Breddin HK, Lippold R, Bittner M, Kirchmaier CM, Krzywanek HJ, Michaelis J.

Spontaneous platelet aggregation as a predictive risk factor for vascular occlusions in healthy volunteers? Results of the HAPARG Study. Haemostatic parameters as risk factors in healthy volunteers. Atherosclerosis. 1999 May;144(1):211-9. PMID: 10381294 [PubMed - indexed for MEDLINE]

18

Lorenz M, Muller M, Jablonka B, Vigh T, Kirchmaier CM.

High doses of methylene blue/light treatment crosslink the A-alpha-subunit of fibrinogen: influence of this photooxidization on fibrinogen binding to platelets. Haemostasis. 1998 Jan-Feb;28(1):17-24. PMID: 9885366 [PubMed - indexed for MEDLINE]

19

Kirchmaier CM, Wolf H, Schafer H, Ehlers B, Breddin HK.

Efficacy of a low molecular weight heparin administered intravenously or subcutaneously in comparison with intravenous unfractionated heparin in the treatment of deep venous thrombosis. Certoparin-Study Group. Int Angiol. 1998 Sep;17(3):135-45. PMID: 9821025 [PubMed - indexed for MEDLINE]

20

Scharrer I, Kirchmaier C.

[Indications for and safety of blood plasma] Internist (Berl). 1998 Jun;39(6):656. German. PMID: 9677527 [PubMed - indexed for MEDLINE]

21

Seifried E, Bialleck H, Weber H, Kirchmaier CM, Waschk E, Marx S, Tschauder S, Roth WK.

[Prevalence of hepatitis G virus genome in blood donors] Beitr Infusionsther Transfusionsmed. 1997;34:11-5. German. PMID: 9417332 [PubMed - indexed for MEDLINE]

22

Schini-Kerth VB, Bassus S, Fisslthaler B, Kirchmaier CM, Busse R.

Aggregating human platelets stimulate the expression of thrombin receptors in cultured vascular smooth muscle cells via the release of transforming growth factor-beta1 and platelet-derived growth factorAB. Circulation. 1997 Dec 2;96(11):3888-96. PMID: 9403612 [PubMed - indexed for MEDLINE]

23

Seidl C, Siehl J, Kirchmaier CM, Seifried E.

Analysis of glycoprotein Ia, Ib, IIb and IV RNA in platelets: quantitative determination using fluorescence-based polymerase chain reaction. Haemostasis. 1997 May-Jun;27(3):131-9. PMID: 9306130 [PubMed - indexed for MEDLINE]

24

Tonn T, Westrup D, Seidl C, Kirchmaier CM, Seifried E.

Sensitive determination of the RhD genotype in mixed samples using fluorescence-based polymerase chain reaction. Vox Sang. 1997;72(3):177-81. PMID: 9145489 [PubMed - indexed for MEDLINE]

25

Eistert B, Kirchmaier C, Risse M, Glanz H.

[Disorders of thrombocyte function as a cause of postoperative hemorrhage after tonsillectomy] HNO. 1995 Mar;43(3):177-81. German. PMID: 7759299 [PubMed - indexed for MEDLINE]

26

Thurmann P, Harder S, Kirchmaier CM.

Influence of piroxicam coadministration on pharmacodynamic parameters and the plasma concentration/effect relationship of recombinant hirudin (CGP 39393). Eur J Clin Pharmacol. 1995;48(3-4):241-6. PMID: 7589048 [PubMed - indexed for MEDLINE]

27

Kirchmaier CM, Lindhoff-Last E, Rubesam D, Scharrer I, Vigh Z, Mosch G, Wolf H, Breddin HK.

Regression of deep vein thrombosis by i.v.-administration of a low molecular weight heparin--results of a pilot study. Thromb Res. 1994 Mar 1;73(5):337-48. PMID: 8016818 [PubMed - indexed for MEDLINE]

28

Spangenberg P, Kirchmaier CM, Schirmer A, Meyer M, Breddin HK.

Functional studies on platelets of a patient with an acquired disorder of platelet function associated with autoantibodies against membrane glycoprotein IIB/IIIA complex. Thromb Res. 1993 Mar 1;69(5):435-42. PMID: 8497859 [PubMed - indexed for MEDLINE]

29

Meyer M, Kirchmaier CM, Schirmer A, Spangenberg P, Strohl C, Breddin K.

Acquired disorder of platelet function associated with autoantibodies against membrane glycoprotein IIb-IIIa complex--1. Glycoprotein analysis. Thromb Haemost. 1991 May 6;65(5):491-6. PMID: 1871709 [PubMed - indexed for MEDLINE]

30

Kirchmaier CM, Bellinger OK, Schulz B, Breddin HK.

Effect of recombinant hirudin on cytosolic Ca2+ concentrations using different platelet stimulators. Haemostasis. 1991;21 Suppl 1:121-6. PMID: 1894187 [PubMed - indexed for MEDLINE]

31

Bellinger OK, Kirchmaier CM, Breddin HK.

[Objective assessment of the risk of edema in patients with venous diseases and healthy vein probands using optoelectronic volumetry] Vasa Suppl. 1991;33:324-6. German. PMID: 1788738 [PubMed - indexed for MEDLINE]

32

Kirchmaier CM, Lindhoff E, Basic-Micic M, Breddin HK.

[Effect of subcutaneous administration of lactobionic acid on coagulation and platelet function] Vasa Suppl. 1991;33:168. German. PMID: 1788660 [PubMed - indexed for MEDLINE]

33

Kirchmaier CM, Altorjay I, Bellinger O, Breddin HK.

[Effect of SIN 1 on the interactions of endothelial cells and thrombocytes] Z Kardiol. 1991;80 Suppl 5:13-6. German. PMID: 1776329 [PubMed - indexed for MEDLINE]

34

Kirchmaier CM, Altorjay J, Bellinger O, Breddin HK.

[Inhibition of induced thrombocyte aggregation in the presence of endothelial cells by dipyridamole] Vasa Suppl. 1991;32:318-21. German. PMID: 1771524 [PubMed - indexed for MEDLINE]

35

Kirchmaier CM, Meyer M, Spangenberg P, Heller R, Haroske D, Breddin HK, Till U.

Platelet membrane defects in fawn hooded bleeder rats. Thromb Res. 1990 Feb 1;57(3):353-60. PMID: 2315892 [PubMed - indexed for MEDLINE]

36

Altorjay I, Kirchmaier CM, Breddin HK.

Changes of spontaneous and induced platelet aggregation in the presence of a human endothelial cell monolayer. Thromb Res. 1989 Jul 1;55(1):69-77. PMID: 2781521 [PubMed - indexed for MEDLINE]

37

Breddin HK, Krzywanek HJ, Althoff P, Kirchmaier CM, Rosak C, Schepping M, Weichert W, Ziemen M, Schoffling K, Uberla K.

Haemostasiological parameters as risk factor for new arterial occlusions in diabetics. Klin Wochenschr. 1986 Oct 15;64(20):1042-6. PMID: 3491249 [PubMed - indexed for MEDLINE]

38

Breddin HK, Krzywanek HJ, Althoff P, Kirchmaier CM, Rosak C, Schepping M, Weichert W, Ziemen M, Schoffling K, Uberla K.

Spontaneous platelet aggregation and coagulation parameters as risk factors for arterial occlusions in diabetics. Results of the PARD-study. Int Angiol. 1986 Jul-Sep;5(3):181-95. PMID: 3104511 [PubMed - indexed for MEDLINE]

39

Breddin HK, Kirchmaier CM.

Substitution of antithrombin III. Wien Klin Wochenschr. 1984 Dec 21;96(24):875-9. PMID: 6528616 [PubMed - indexed for MEDLINE]

40

Leuschner U, Baumgartel H, David R, Kirchmaier CM, Hagenmuller F, Sieratzki J, Hubner K.

Biochemical and morphological investigations of the toxicity of a Capmul preparation and a bile salt-EDTA solution in patients with bile duct stones. Am J Gastroenterol. 1984 Apr;79(4):291-8. PMID: 6424434 [PubMed - indexed for MEDLINE]

41

Breddin K, Bender N, Kirchmaier CM.

On the mechanism of platelet activation during hemostasis and thrombosis and on the effects of platelet inhibiting drugs. Adv Exp Med Biol. 1984;164:145-54. No abstract available. PMID: 6421101 [PubMed - indexed for MEDLINE]

42

Truber E, Kirchmaier CM, Wurbs D.

[Nonocclusive mesenteric ischemia (author's transl)] Radiologe. 1981 Aug;21(8):391-5. German. PMID: 7280220 [PubMed - indexed for MEDLINE]

43

Kirchmaier CM, Bender N, Sayegh AA, Breddin K.

A platelet stimulating fraction in human and animal tissues. Artery. 1980;8(5):416-21. PMID: 6971084 [PubMed - indexed for MEDLINE]

44

Bender N, Kirchmaier C, Bartsch B, Lindenborn D, Breddin K.

Stimulation of blood platelets by extracts of subcutaneous tissue. Thromb Res. 1979 Feb-Mar;14(2-3):341-51. PMID: 442011 [PubMed - indexed for MEDLINE]

45

Kirchmaier C, Bender N, Wilhelm B, Sayegh AA, Breddin K.

A hemostasis activating factor (HAF) in subcutaneous tissue extracts: effects on morphologic platelet changes, platelet retention and platelet aggregation. Thromb Res. 1979;16(1-2):81-91. PMID: 505430 [PubMed - indexed for MEDLINE]

46

Scharrer I, Pander U, Kirchmaier C, Rufer A, Maas C.

[The behavior of factor VIII associated antigen, platelet retention and thrombocyte aggregation in patients with vascular diseases] Verh Dtsch Ges Inn Med. 1978;(84):1373-5. German. PMID: 741969 [PubMed - indexed for MEDLINE]

47

Kirchmaier CT.

The medical examiner's and attending physician's statements. Proc Annu Meet Med Sect Am Life Conv. 1965;53:107-22. PMID: 5899826 [PubMed - indexed for MEDLINE]